| 越婢加术汤对肾炎模型大鼠的药效学研究 |
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| 引用本文： | 陈淑欣,魏东华,刘秀芹,史静杰.越婢加术汤对肾炎模型大鼠的药效学研究[J].成都中医药大学学报,2011,0(3):38-40. |
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| 作者姓名： | 陈淑欣 魏东华 刘秀芹 史静杰 |
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| 作者单位： | 1. 哈尔滨医科大学大庆校区,黑龙江大庆,163319
2. 大庆市药品检验所,黑龙江大庆,163316 |
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| 基金项目： | 黑龙江省中医药管理局课题(编号:ZHY08-Z82); 黑龙江卫生厅课题(编号:2009-259) |
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| 摘 要： | 目的：观察越婢加术汤对模型大鼠的治疗作用，评价及探索越婢加术汤中白术的提取工艺对大鼠Heymann肾炎的影响，确定越婢加术汤的有效部位。方法：给大鼠腹腔注射同种肾脏免疫复合物，复制大鼠主动型Heymann肾炎模型，分为Heymann肾炎模型组、越婢加术提取物组和地塞米松组，同时设立空白对照组。分别测定其24h尿蛋白，血...
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| 关 键 词： | 越婢加术汤 肾炎模型大鼠 药效学 |
Pharmacodynamics of Yuepi Jiazhu Decoction on Active Heymann Nephritis in Rats |
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| CHEN Shun-xin,WEI Dong-hua,LIU Xiu-qin,et al.Pharmacodynamics of Yuepi Jiazhu Decoction on Active Heymann Nephritis in Rats[J].Journal of Chengdu University of Traditional Chinese Medicine,2011,0(3):38-40. |
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| Authors: | CHEN Shun-xin WEI Dong-hua LIU Xiu-qin |
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| Institution: | CHEN Shun-xin,WEI Dong-hua,LIU Xiu-qin,et al(Daqing Branch of HarBin Medical University,Daqing 163319,Daqing drug control institute,Daqing 163319) |
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| Abstract: | Objective: To study the effect of active parts from Atractylodis Macrocephalae Rhizoma in the Yuebijiazhu decoction on active Heymann nephritis(AHN) in rats.Method: The rat models of AHN were induced by intra-peritioneal administration of kidney homogenate and Freund's adjuvant.AHN rats were divided into three groups: AHN model group,extract of Yuebijiazhu group and dexamethasone group.The control group was only given normal saline solution.Measured 24h urinary protein,hematuria,serum urea nitrogenetc.Resul... |
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| Keywords: | Yuebijiazhu decoction heymann nepyritis in rats pharmacodynamics |
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