静脉吸毒致感染性心内膜炎5例临床分析

目的分析静脉吸毒致感染性心内膜炎(IE)的临床特征及其诊断要点.方法回顾分析该院近5年收治的5例静脉吸毒致IE的临床资料.结果IE由静脉吸毒引起者占4.6%,5例患者均累及三尖瓣/肺动脉瓣,所有患者都有咳嗽、胸病症状及胸片肺部斑片状阴影,2例血培养阳性者均为金黄色葡萄球菌.4例经抗生素治疗好转,1例手术治疗治愈.结论静脉吸毒致IE多为右心IE,致病菌多为金黄色葡萄球菌,均有肺部感染或肺栓塞.经敏感抗生素或手术治疗预后相对良好.

Clinical analysis of 5 cases of venous drug-habit infective endocarditis

Objective: To analyze the clinical characteristics and diagnosis of venous drug-habit infective endocarditis(IE). Methods: We retrospectively analyzed 5 cases of venous drug-habit infective endocarditis in the last 5 years.Results: The incidence of venous drug-habit IE was 4.6%. Tricuspidal/pulmonary valve was infected in all 5 cases. 2 cases blood culture were positive, the majority of IE were caused by staphylococci. All patients coughed and felt chest pain, and shadow was found in all 5 X-ray of lung. All patients were treated with antimicrobials, one patient also with surgery, and they were cured. Conclusions: Most venous drug-habit IE are right-sided IE. Most pathogens are staphylococci. All patients had lung infection and pulmonary embolism.The prognosis is good by therapyed with antimicrobials or surgery.