急性胰腺炎患者病因及胰腺外损害的临床分析

目的探讨急性胰腺炎(Acute pancreatitis,AP)患者病因及胰腺外损害的临床特征。方法分析59例AP患者的病历资料,观察其病因、胰腺外损害的临床特征以及预后的关系。结果59例AP患者以胆源性病因为主,占66.1%。其次是饮酒及饮食因素。78.6%的AP患者合并胰腺外损害,且胰腺外损害部位依次为肝脏74.6%、呼吸道18.6%、胃肠道11.8%。肾功能不全、心功能不全、胰性脑病等较少见。其中28.1%的AP患者合并2种或2种以上器官受损,与无胰腺外损害的AP患者相比,病死率升高、住院天数明显延长。结论AP是一种可累及多系统的疾病,合并胰腺外损害者病死率升高,恢复较慢。

Etiology and clinical features in patients with of extra-pancreatic impairment acute pancreatitis

Objective To study the etiology and clinical features of extra-pancreatic impairment in patients with acute pancreatitis(AP).Methods Medical history materials of 59 patients with AP were studied retrospectively.The etiology,clinical features of extra-pancreatic impairment and prognosis of these patients were observed.Results Of the 59 patients,biliary disease was the most common cause of AP(66.1%).The other factors were inappropriate diet and alcoholic.Patients with extra-pancreatic impairment accounted for 78.6% of all the patients.And liver malfunction was the most frequent extra-pancreatic impairment(74.6 %),followed by respiratory (18.6 %),gastroenteric impairment(11.8 %).Renal malfunction,heart malfunction and pancreatic encephalopathy occurred rarely.28.1% patients with AP had two or more extra-pancreatic impairment.Compared with patients without extra-pancreatic impairment,the death rate of patients with extra-pancreatic impairment was higher,and the hospitalization duration was longer(P<0.05).Conclusion AP is a disease affecting multiple system and organs.AP patients with extra-pancreatic impairment often have a high mortality and slow recovery.