| 肌电图引导下不同剂量肉毒素治疗痉挛性脑瘫的疗效观察 |
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| 引用本文： | 彭桂兰,蔡淑英. 肌电图引导下不同剂量肉毒素治疗痉挛性脑瘫的疗效观察[J]. 临床儿科杂志, 2011, 29(11). DOI: 10.3969/j.issn.1000-3606.2011.11.022 |
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| 作者姓名： | 彭桂兰 蔡淑英 |
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| 作者单位： | 厦门市妇幼保健院儿童神经康复科,福建厦门,361003 |
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| 摘 要： | 目的观察肌电图引导下靶肌肉注射不同剂量A型肉毒素(BTX-A)治疗儿童痉挛型脑瘫疗效。方法选择痉挛性脑瘫病例90例,分为3组,肌电图引导下定位,BTX-A痉挛肌肉局部注射,A组3 U/kg,B组4 U/kg,C组5 U/kg。注射后配合康复训练,采用粗大运动评价量表(GMFM)评价患儿功能区的运动功能,采用改良Ashworth痉挛量表评价肌痉挛程度,随访1、2、3个月的疗效。结果各组治疗后GMFM评分增加,Ashworth分级减轻与治疗前比较差异有统计学意义(P均<0.05);但不同剂量BTX-A组在治疗后的GMFM评分、Ashworth分级各组差异无统计学意义(P均>0.05)。结论肌电图定位下BTX-A剂量在3～5 U/kg之间治疗后各项疗效指标改善,不同剂量疗效差异无统计学意义。
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| 关 键 词： | 脑性瘫痪 痉挛 肉毒素 肌电图 儿童 |
A clinical study on the therapeutic effects of injection with botulinum toxin A under direction of electromyography in treating spastic cerebral palsy |
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| PENG Gui-lan,CAI Shu-ying. A clinical study on the therapeutic effects of injection with botulinum toxin A under direction of electromyography in treating spastic cerebral palsy[J]. The Journal of Clinical Pediatrics, 2011, 29(11). DOI: 10.3969/j.issn.1000-3606.2011.11.022 |
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| Authors: | PENG Gui-lan CAI Shu-ying |
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| Affiliation: | PENG Gui-lan,CAI Shu-ying(Department of Neurological Rehabilitation,Xiamen Maternity and Child Health Care Hospital,Xiamen 361003,Fujian,China) |
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| Abstract: | Objective To evaluate the therapeutic effect of injections with Botulinum toxin A(BTX-A)under direction of electromyography in treating spastic cerebral palsy children.Methods Ninety spastic cerebral palsy children were equally divided into three groups:group A,group B and group C.They were injected with BTX-A at several muscular sites under the direction of electromyography.Three different doses of BTX-A were administered to different groups(group A:3 U/kg;group B:4 U/kg;group C:5 U/kg).The Gross Motor Ass... |
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| Keywords: | cerebral palsy spasticity botulinum toxin electromyography child |
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