| 18F-FDG PET用于头颈部肿瘤疗效评价和预后分析的研究进展 |
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| 引用本文： | 刘森,于金明,李金丽.18F-FDG PET用于头颈部肿瘤疗效评价和预后分析的研究进展[J].中华肿瘤防治杂志,2005,12(5):391-394. |
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| 作者姓名： | 刘森 于金明 李金丽 |
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| 作者单位： | 山东省肿瘤医院放疗科,山东,济南,250117 |
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| 摘 要： | 正电子发射型计算机断层显像(positron emission tomograph,PET)通过探测肿瘤标准摄取值(standard uptake value,SUV)的大小来判断肿瘤的良恶性、生物学行为、监测放化疗的疗效和早期发现肿瘤的复发等.18F-脱氧葡萄糖(18F-FDG)是目前最常用的PET显像药物,主要反映细胞的葡萄糖代谢情况,18F-FDG的吸收与肿瘤生物学行为、代谢特征、病理学类型及分化程度的相关性为临床判断肿瘤的恶性程度提供了一定的依据,进而为反映肿瘤的预后提供了分子基础.综述了18F-FDG PET在头颈部肿瘤疗效评价和预后分析的研究进展.
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| 关 键 词： | 头颈部肿瘤 体层摄影术 发射型计算机 脱氧葡萄糖 预后 |
| 文章编号： | 1009-4571(2005)05-0391-04 |
| 修稿时间： | 2004年8月2日 |
Progress of 18F-FDG PET in evaluating curative effect and prognosis of head and neck cancer |
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| LIU Sen,YU Jin-ming,LI Jin-li.Progress of 18F-FDG PET in evaluating curative effect and prognosis of head and neck cancer[J].Chinese Journal of Cancer Prevention and Treatment,2005,12(5):391-394. |
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| Authors: | LIU Sen YU Jin-ming LI Jin-li |
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| Institution: | LIU Sen,YU Jin-ming,LI Jin-li Department of Radiotherapy,Shandong Tumor Hospital,Jinan 250117,P.R.China |
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| Abstract: | Positron emission tomography (PET) can track tumor biological and metabolic changes caused by therapy or by disease progression. 18F-FDG, a ghulose analogue, is the most commanly used PET tracer in clinical practice and it reflects glucose metablism of the cell. 18F-FDG PET has been used for the early assessment of subclinical tumor response, the evaluation of therapy after its completion and the detection of viable recurrent or relapsing tumor. This review attempts to summarize the current data available on the role of 18F-FDG PET in evaluating the curative effect and prognosis of head and neck cancer. |
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| Keywords: | head and neck neoplasms tomography emission computed deoxyglucose prognosis |
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