夜戴型角膜塑形镜矫治青少年近视的临床观察研究

目的 观察青少年近视患者配戴夜戴型角膜塑形镜(Ortho-KCL)后裸眼视力、角膜曲率、角膜厚度、眼轴长度的变化.方法 应用欧普康视科技股份有限公司提供的梦戴维夜戴型角膜塑形镜,对2010年6月至2012年6月于第二军医大学长征医院门诊就诊并随访的近视度数＜-6.00 D的50例患者(100眼)进行矫治.采用综合验光仪检测患者配戴前和配戴3、6、12、24个月后的裸眼视力,角膜地形图检测角膜曲率和角膜厚度,眼科A/B超测量眼轴长度.结果 患者配戴夜戴型角膜塑形镜3、6、12、24个月后裸眼视力较戴镜前均稳定提高;角膜曲率平均K值均减小(P均＜0.01).左右眼配戴夜戴型角膜塑形镜3、6、12、24个月后角膜厚度与戴镜前相比均无明显改变(P均＞0.05);眼轴长度略增加,但与戴镜前比较差异均无统计学意义(P均＞0.05).结论 配戴夜戴型角膜塑型镜能够有效提高近视青少年的裸眼视力,有效、安全地减缓近视发展.

Clinical study of night-wear orthokeratology in treatment of adolescent patients with myopia

Objective To observe the changes of uncorrected visual acuity, corneal curvature, corneal thickness and axial length in adolescent patients with myopia after wearing night-wear orthokeratology lens (Ortho-KCL). Methods Fifty adolescent patients (100 eyes) with degree of myopia <-6.00 D in Changzheng Hospital of Second Military Medical University were treated by wearing night-wear orthokeratology lens (Autek China Inc.) from Jun. 2010 to Jun. 2012. The uncorrected visual acuities of patients were measured by phoropter before treatment and on 3^rd, 6^th, 12^th and 24^th months after treatment, the corneal curvature and corneal thickness was measured by corneal topography, and the axial length was measured by A/B ultrasonic diagnostic system. Results The ucorrected visual acuities of patients at 3, 6, 12 and 24 months after treatment were increased compared with that before treatment, and the average K values of corneal curvature were significantly decreased (all P<0.01); the axial lengths were slightly increased, but the differences were not statistically significant (all P>0.05). There was no significant difference in corneal thickness of patients before and after treatment. Conclusion Night-wear orthokeratology can improve the uncorrected vision of adolescent patients with myopia, and can effectively and safely slow down the progression of myopia.