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| 小儿鼾症手术前后血浆生物标志物的变化及临床意义 | |
| 引用本文： | 万玉峰,刘业海,胡晓春,刘龙生. 小儿鼾症手术前后血浆生物标志物的变化及临床意义[J]. 安徽医科大学学报, 2015, 0(6): 876-878 |
| 作者姓名： | 万玉峰 刘业海 胡晓春 刘龙生 |
| 作者单位： | 安徽医科大学附属巢湖医院耳鼻咽喉科,合肥,238000;安徽医科大学第一附属医院耳鼻咽喉 - 头颈外科,合肥,230022 |
| 基金项目： | 安徽高校省级自然科学研究项目 |
| 摘 要： | 探讨小儿鼾症患者行扁桃体和（或）腺样体手术对与心血管疾病密切相关的血浆生物标志物的影响。选取单纯非肥胖型小儿鼾症患者20例，进行术前和术后6个月血浆超敏 C 反应蛋白（hs-CRP）、肿瘤坏死因子α（TNF-α）、白介素6（IL-6）、脂联素和胎球蛋白 A 的水平的测定，结果显示术后6个月的血浆 hs-CRP、TNF-α、IL-6、脂联素的水平均明显低于相应的术前水平（P <0.001），胎球蛋白 A 的水平均明显高于相应的术前水平（P <0.001）。小儿鼾症患者进行扁桃体和（或）腺样体切除术有助于降低其并发心血管疾病的风险。 |
| 关 键 词： | 小儿鼾症 扁桃体和(或)腺样体切除术 血浆生物标志物 |
The clinical significance and change of plasma biomarkers before and after operation in children snoring patients |
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| Abstract: | Abstrct To investigate the impact of tonsils and / or adenoidectomy on the plasma biomarkers closely related with the cardiovascular disease in snoring children. 20 patients in snoring children were recruited. Preoperative values of the levels of plasma biomarkers(hs-CRP,TNF-α,IL-6,adiponectin,fetuin-A)of the participants were recorded preoperatively and at postoperative 6 months( tonsils and / or adenoidectomy). Results showed the levels of hs-CRP,TNF-α,IL-6 and adiponectin were significantly lower than the corresponding levels of preoperative,whereas the levels of fetuin-A increased remarkbly(P < 0. 05). The risks of development of cardiovascular disease are de-creased in association with tonsils and / or adenoidectomy in snoring children. |
| Keywords: | children snoring disease tonsils and/or adenoidectomy plasma biomarkers |
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