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Multiphasic presentation of Rasmussen's encephalitis
Authors:Andreja Avberšek  Anna Miserocchi  Andrew W. McEvoy  Ayesha V. Patel  Eleonora Aronica  Ingmar Blümcke  Thomas S. Jacques  James Acheson  Maria Thom  Sanjay M. Sisodiya
Affiliation:1. Department of Clinical and Experimental Epilepsy, Institute of Neurology, UCL Institute of Neurology, Queen Square, London;2. Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London;3. Aston University, Birmingham, United Kingdom;4. Department of (Neuro)Pathology, Academic Medical Center, Swammerdam Institute for Life Sciences, Center for Neuroscience, University of Amsterdam;5. SEIN ‐ Stichting Epilepsie Instellingen Nederland, Heemstede, The Netherlands;6. Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany;7. Developmental Biology and Cancer Programme, UCL Institute of Child Health and Department of Histopathology, Great Ormond Street Hospital for Children NHS Foundation Trust, London;8. Department of Neuro‐Ophthalmology, National Hospital for Neurology and Neurosurgery, Queen Square, London;9. Department of Neuropathology, UCL Institute of Neurology, Queen Square, London, United Kingdom
Abstract:Rasmussen's encephalitis is a rare, chronic inflammatory disorder of unknown cause, characterised by drug‐resistant focal epilepsy that may rarely present in adolescence or adulthood. We present a case of Rasmussen's encephalitis with prominent recurrent fluctuation in symptoms and well‐documented fluctuating changes on MRI, adding to the spectrum of diversity of Rasmussen's encephalitis.
Keywords:encephalitis  magnetic resonance imaging  fluctuation
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