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复方寄生流浸膏对高血压动物模型降压作用的研究
引用本文:叶芳,鲜万华,李淑玲,杨竟.复方寄生流浸膏对高血压动物模型降压作用的研究[J].上海中医药杂志,2004,38(9):53-55.
作者姓名:叶芳  鲜万华  李淑玲  杨竟
作者单位:山东大学齐鲁医院,山东,济南,250012
基金项目:山东省科委资助项目 (99- 2 - 37- 6 )
摘    要:为探讨复方寄生流浸膏(主药:桑寄生、淫洋藿、女贞子、生黄芪、泽泻等)治疗高血压的疗效,观察该药单次用药与连续14d用药对自发性高血压大鼠(SHR)和肾性高血压模型犬(RHD)的降压作用,并与牛黄降压丸、硝苯地平胶囊比较。结果:复方寄生流浸膏对SHR和RHD单次给药和多次给药均有显著的降压作用;这种作用起效缓慢,但维持时间相对较长;在一定剂量范围内呈明显的量效关系。提示该药有降压作用。

关 键 词:复方寄生流浸膏  高血压  动物模型
文章编号:1007-1334(2004)09-0053-03
修稿时间:2004年6月16日

Hypotensive Effects of "Fufang Jisheng Fluid" on Hypertensive Animals
YE Fang,XIAN Wan-hua,LI Shu-ling,YANG JingQilu Hospital of Shandong University.Hypotensive Effects of "Fufang Jisheng Fluid" on Hypertensive Animals[J].Shanghai Journal of Traditional Chinese Medicine,2004,38(9):53-55.
Authors:YE Fang  XIAN Wan-hua  LI Shu-ling  YANG JingQilu Hospital of Shandong University
Institution:YE Fang XIAN Wan-hua LI Shu-ling YANG JingQilu Hospital of Shandong University
Abstract:To observe the hypotensive effects of "Fufang Jisheng Fluid" in the treatment of hypertension, single administration and14-day consecutive administration of the Fluid were adopted to treat spontaneous hypertensive rats (SHR) and renal hypertensive dogs (RHD). "Niuhuang Jiangya Pill" and Nifedipine were used as control. Results: single administration and14-day consecutive administration of the Fluid could reduce the blood pressure, nevertheless, it acted slowly and lasted a long time, displaying a quantity-effect relationship within certain dosage. It is confirmed that the Fluid can reduce blood pressure.
Keywords:Fufang Jisheng Fluid"  hypertension  animal model
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