Correlation between CSWS and aphasia in Landau-Kleffner syndrome: A study of three cases |
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| Affiliation: | 1. Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan;2. Department of Food Science, Center of Excellence for the Oceans, National Taiwan Ocean University, Keelung, Taiwan |
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| Abstract: | We report three typical cases of Landau-Kleffner syndrome with varied courses. The very frequent discharges in sleep EEGs, often showing the patterns of CSWS (continuous spike-waves during slow-wave sleep), either typical (spike-wave complex occupying over 85% of slow-wave sleep duration) or atypical (spike-waves occupying less than 85% of slow-wave sleep), were presented in all our cases. The CSWS seems correlated with aphasia in our cases. Since the disappearance of CSWS might be indicative of a lagged improvement in aphasia, we suggest that sufficiently long-term treatment with anticonvulsants and/or corticosteroids is worthwhile, if the EEG is improved significantly by this treatment. |
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