Inhibition of herpes simplex virus type 1 by aqueous extracts from shoots of Helichrysum aureonitens (Asteraceae) |
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| Affiliation: | 1. Department of Botany, University of Pretoria, Pretoria 0002, South Africa;2. Department of Medical Virology, Institute of Pathology, University of Pretoria, P.O. Box 2034, Pretoria 0001, South Africa;1. Geological Survey of Denmark and Greenland (GEUS), Øster Voldgade 10, DK-1350 Copenhagen K, Denmark;2. School of Pharmacy, University of Oslo, P.O. Box 1068 Blindern, N-0316 Oslo, Norway;3. Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, N-0315 Oslo, Norway;1. Institute for Microbiology, Ernst-Moritz-Arndt University, Greifswald, Germany;2. Department of Genomic and Applied Microbiology & Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg-August-University Göttingen, Göttingen, Germany;3. Institute of Biochemistry, Ernst-Moritz-Arndt University, Greifswald, Germany;4. Department of Chemistry and Biotechnology, Aachen University of Applied Sciences, Heinrich-Mußmannstr. 1, 52428 Jülich, Germany;5. AB Enzymes GmbH, Darmstadt, Germany;1. Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA;2. Harvard Ph.D. Program in Virology, Division of Medical Sciences, Harvard University, Boston, MA 02115, USA;3. Department of Botany, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada |
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| Abstract: | ![]()
Helichrysum aureonitens, a southern African medicinal plant reported to have antibacterial properties, was evaluated for antiviral activity against herpes simplex virus type 1 (HSV-1) in vitro. The crude aqueous extract from shoots of H. aureonitens at a concentration of 1.35 mg/ml (w/v) showed significant antiviral activity on HSV-1 in human lung fibroblasts as demonstrated by the absence of a cytopathic effect. |
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