Abdominal fat distribution measured by ultrasound and aerobic fitness in young Danish men born with low and normal birth weight |
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Authors: | Louise G. Grunnet Anne-Sofie Q. Lund Klaus K. Laigaard Amra Ciric Alibegovic Rasmus T. Jensen Nicolai S. Henriksen Arne Astrup Allan Vaag Charlotte Brøns |
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Affiliation: | 1. Steno Diabetes Center, Gentofte, Denmark;2. Department of Endocrinology, Rigshospitalet, Copenhagen, Denmark;3. Department of Nutrition, Exercise and Sports (NEXS), University of Copenhagen, Denmark;4. Cardiovascular and Metabolic Disease (CVMD) Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden |
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Abstract: | Abdominal subcutaneous and visceral adipose tissue thickness was examined by ultrasound in 17 men with low birth weight (LBW) and 26 with normal BW control individuals to determine if abdominal obesity in LBW individuals is due to increased visceral or subcutaneous fat mass/thickness, or both. Men born with LBW had an increased waist-to-hip ratio (P = 0.04), greater abdominal fat thickness (P = 0.05) and increased visceral (VAT) and subcutaneous adipose tissue (SAT) thickness compared with controls, however the latter not statistically significant (P = 0.08, P = 0.10). A significant difference between birth weight groups in both SAT (P = 0.04) and VAT (P = 0.03) was found after adjustment for weight, whereas no significant difference in either SAT (P = 0.93) or VAT (P = 0.30) was found after adjustment for BMI. Increased waist-to-hip ratio in LBW individuals is due to increased total abdominal fat including both subcutaneous and visceral fat. |
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Keywords: | Corresponding author at: Department of Endocrinology, Rigshospitalet, Tagensvej 20, 2200 Copenhagen N, Denmark. Low birth weight Visceral fat Subcutaneous fat Ultrasound method Abdominal fat |
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