| 微孔表涂植入体与股骨界面生物学特性的实验研究 |
| |
| 引用本文： | 齐新生,李雪松,陈辉,孔翔飞,李永刚. 微孔表涂植入体与股骨界面生物学特性的实验研究[J]. 江苏医药, 2003, 29(2): 103-104,F003 |
| |
| 作者姓名： | 齐新生 李雪松 陈辉 孔翔飞 李永刚 |
| |
| 作者单位： | 210009,南京,东南大学附属中大医院骨科;哈尔滨医科大学第一附属医院骨科 |
| |
| 基金项目： | 铁道部科技基金资助项目 (J94Z0 13) |
| |
| 摘 要： | 目的比较金属与羟基磷灰石(hydroxyapatite,HA)微孔表涂股骨植入体与骨界面的生物学持性。方法用等离子喷涂技术,将表面分别喷涂HA和钴铬钼合金微粒的不锈钢三棱针配对植入20只成年家免的股骨,饲养2个月。采用X线摄片、光镜检查和能谱分析对二者进行比较。结果HA表涂植入体周围有较多的成骨反应,透亮区较金属表涂的植入体较少而窄,有较强的四环素荧光带,组织学检查HA表涂植入体周围以骨组织为主,钴铬钼合金表涂植入体以纤维组织为主。能谱分析以HA植入体与周围组织交接部含钙量为高。结论植入兔的股骨两个月后,HA微孔表涂植入体的生物学特性较金属微孔表涂植入体更有利于生物学的固定。
|
| 关 键 词： | 多孔表面植入体 羟基磷灰石 组织学 |
Experimental study of porous coating femur implants |
| |
| QI Xinsheng,LI Xuesong,CHEN Hui,et al.. Experimental study of porous coating femur implants[J]. Jiangsu Medical Journal, 2003, 29(2): 103-104,F003 |
| |
| Authors: | QI Xinsheng LI Xuesong CHEN Hui et al. |
| |
| Affiliation: | QI Xinsheng,LI Xuesong,CHEN Hui,et al. Department of Orthopaedics,the Affiliated Zhongda Hospital,Southeast University,Nanjing 210009 |
| |
| Abstract: | Objective To compare the biologic characteristics of interface of femur implants of HA porous coating to bone with that of metal porous coating.Methods Forty triangular nails with HA or Co Cr Mo alloy coating by the plasma sprayed technology were implanted in pair into the bilateral femurs of 20 adult rabbits via the top of greater trochanters.The animals were killed 2 months later.X ray examination,histoogic observation,and energy analysis were made.Results The HA coating implants had significantly more new bone formation,more strong fluorescenceline,and less radiolucency zone than the Co Cr Mo alloy coating implants.Conclusion The femur implants of HA coating were more osteoconductive than the Co Cr Mo alloy coating in rabbits. |
| |
| Keywords: | Porous coating implants Hydroxyapatites Histology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
