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老年性聋部分致病机制和干预的研究进展
引用本文:王健艳,谭静芊,杨洛盈,陈愈彬,李永奇,李鹏. 老年性聋部分致病机制和干预的研究进展[J]. 中华耳科学杂志, 2021, 0(1): 151-156
作者姓名:王健艳  谭静芊  杨洛盈  陈愈彬  李永奇  李鹏
作者单位:中山大学附属第三医院耳鼻咽喉头颈外科
基金项目:广州市科技计划资助项目(201803010093);中山大学重点发展项目(201812281965)。
摘    要:目的 随着社会的逐渐老龄化,老年性聋的发病率越来越高,本篇综述旨在探讨老年性聋的最新发病机制、治疗及干预等,为未来的研究方向提供参考.方法 在Pubmed,Web Science,Medline,中国知网,万方等数据库搜索老年性耳聋致病机制、预防的相关文献并进行系统分析、归纳总结.结果 本文共引用了41篇文献资料,发现...

关 键 词:老年性聋  发病机制  干预  治疗

Advances in Research on Pathogenic Mechanisms and Interventions of Presbycusis
WANG Jianyan,TAN Jingqian,YANG Luoying,CHEN Yubin,LI Yongqi,LI Peng. Advances in Research on Pathogenic Mechanisms and Interventions of Presbycusis[J]. Chinese Journal of Otology, 2021, 0(1): 151-156
Authors:WANG Jianyan  TAN Jingqian  YANG Luoying  CHEN Yubin  LI Yongqi  LI Peng
Affiliation:(Department of Otorhinolaryngology Head and Neck Surgery,Third affiliated Hospital of Sun Yat-Sen University,Guangzhou,China,510630)
Abstract:Objectives Along with increasing aging of the society,the prevalence of presbycusis is also increasing.The purpose of this review is to summarize latest findings regarding pathogenesis,treatments and interventions in presbycusis,so as to provide a basis for for future research.Methods Databases including Pubmed,Web Science,Medline,CNKI and Wanfang were searched for literatures on the pathogenesis and prevention of presbycusis,which were then systematically analyzed and summarized.Results A total of 41 studies were cited in this paper.Prevalence of presbycusis was found to be associated with mitochondrial metabolism and chronic inflammation,and its prevention and treatment of presbycusis may be started with anti-aging,anti-inflammation and music therapies.Conclusion Although many achievements have been made in the research on pathogenesis and prevention of presbycusis,much remains to be understood.There lack major breakthroughs in the study of genes related to age-related deafness.
Keywords:Presbycusis  Pathogenesis  Interventions  Treatments
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