Abstract: | We report on a 14-year-old boy with acute lymphoblastic leukemia (lymphomaleukemia) who had two episodes of acute tumor lysis syndrome during induction of remission with oral prednisolone alone and oral prednisolone, intravenous vincristine, and doxorubicin, respectively. Subsequently he had severe hyperphosphatemia (29.3 and 14.1 mg/dl; 9.46 and 4.55 mmol/L), hypocalcemia, hyperuricemia, hyperkalemia, and azotemia. Multiple stones and tumor cells infiltration were demonstrated in both kidneys. He responded favorably to hemodialysis. © 1995 Wiley-Liss, Inc. |