No evidence for allelic association between bipolar disorder and monoamine oxidase a gene polymorphisms |
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| Authors: | Nick Craddock Johanna Daniels Enriqueta Roberts Mark Rees Peter McGuffin Michael J. Owen |
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| Affiliation: | 1. Departments of Psychological Medicine, University of Wales College of Medicine, Cardiff, United Kingdom;2. Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri |
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| Abstract: | ![]()
We have tested the hypothesis that DNA markers in the MAOA gene show allelic association with bipolar affective disorder. Eighty-four unrelated Caucasian patients with DSM III-R bipolar disorder and 84 Caucasian controls were typed for three markers in MAOA: a dinucleotide repeat in intron 2, a VNTR in intron 1, and an Fnu4HI RFLP in exon 8. No evidence for allelic association was observed between any of the markers and bipolar disorder. © 1995 Wiley-Liss, Inc. |
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| Keywords: | bipolar disorder monoamine oxidase association study affective disorders |
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