|
|||||
|
|
| 药物在室内自然光照射下的贮存期预测方法研究 | |
| 引用本文： | 詹先成,米光辉,殷恭宽,马宝忠,罗光伟. 药物在室内自然光照射下的贮存期预测方法研究[J]. 药学学报, 1995, 30(4): 298-301 |
| 作者姓名： | 詹先成 米光辉 殷恭宽 马宝忠 罗光伟 |
| 作者单位： | 成都华西医科大学药学院 |
| 摘 要： | 以己酸孕酮注射液为例,研究了药物在自然光和不同灯光照射下的含量变化规律,预测了药物在室内自然光照射下的贮存期。找出了不同光源对药物稳定性影响的等效数量关系,使在今后的研究中可以用灯光为光源预测药物在室内自然光照射下的贮存期。己酸孕酮注射液在光照试验中含量变化服从零级反应规律:C=C0-K(Et),在室内自然光照射下的贮存期约为1.9年。 |
| 关 键 词： | 光稳定性 贮存期预测 己酸孕酮 |
| 收稿时间： | 1994-06-23 |
STUDY ON SHELF-LIFE PREDICTION OF DRUGS UNDER INDOOR NATURAL LIGHHT IRRADIATION |
|
| XC Zhan,GH Mi,GK Yin,Bz Ma and GW Luo. STUDY ON SHELF-LIFE PREDICTION OF DRUGS UNDER INDOOR NATURAL LIGHHT IRRADIATION[J]. Acta pharmaceutica Sinica, 1995, 30(4): 298-301 | |
| Authors: | XC Zhan GH Mi GK Yin Bz Ma GW Luo |
| Abstract: | The photodegradation of drugs under natural light and various lamp lightirradiation was studied and the shelf-life of drugs under indoor natural light irradiation was predictedwith hydroxyprogesterone caproate injection as an example.The equivalent influences of differentlight sources on the photostability of the above drug were obtained.Therefore,the natural lightphotostability and the shelf-life of drugs under indoor natural light irradiation can be studied with lamplight exposure experiment.The photodegradation of hydroxyprogesterone caproate injection obeys zero order kinetics :C=C0-kEt,and its shelf-life under indoor natural light irradiation is about 1.9 years. |
| Keywords: | Photostability Shelf-life prediction Hydroxyprogesterone caproateUndergraduate student |
| 本文献已被 CNKI 维普 等数据库收录！ | |
| 点击此处可从《药学学报》浏览原始摘要信息 | |
| 点击此处可从《药学学报》下载全文 | |