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紫外分光光度法测定特美肤涂剂中丙酸氯倍他索的含量
引用本文:计佩影,王增寿,朱光辉. 紫外分光光度法测定特美肤涂剂中丙酸氯倍他索的含量[J]. 中国药房, 2006, 17(2): 136-137
作者姓名:计佩影  王增寿  朱光辉
作者单位:温州医学院附属第二医院药剂科,温州市,325027
摘    要:目的:建立测定特美肤涂剂中丙酸氯倍他索含量的快速方法。方法:采用紫外分光光度法,检测波长为240nm。结果:丙酸氯倍他索检测浓度在12~18μg/ml范围内与吸收度线性关系良好;日内、日间平均回收率分别为99.87%(RSD=1.21%)、99.79%(RSD=1.01%)。结论:本方法简便、快速、准确,尤其适用于未购置高效液相色谱仪的基层医院。

关 键 词:紫外分光光度法  特美肤涂剂  丙酸氯倍他索  含量
文章编号:1001-0408(2006)02-0136-02
收稿时间:2005-02-27
修稿时间:2005-04-04

Content Determination of Clobetasol Propionate in Temeifu Pigmentum by UV Spectrophotometry
JI Peiying,WANG Zengshou,ZHU Guanghui. Content Determination of Clobetasol Propionate in Temeifu Pigmentum by UV Spectrophotometry[J]. China Pharmacy, 2006, 17(2): 136-137
Authors:JI Peiying  WANG Zengshou  ZHU Guanghui
Affiliation:Dept.of Pharmacy, The Second Affiliated Hospital of Wenzhou Medical College,Wenzhou 325027,China
Abstract:OBJECTIVE:To establish a method for quick content determination of clobetasol propionate in temeifu pigmentum.METHODS:UV spectrophotometry was used,and the determination was performed at the wavelength of 240nm.RES-ULTS:The detectable concentration of clobetasol propionate have a good linear relationship with its absorbability in the range of 12~18μg/ml.The inter-day and intra-day average recoveries were 99.87%(RSD=1.21%) and 99.79%(RSD=1.01%),respectively.CONCLUSIONS:The present method is rapid and accurate,which can be widely used in small hospitals not equipped with high performance liquid chromatography.
Keywords:UV speetrophotometry  Temeifu pigmentum  Clobetasol propionate  Content
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