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The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China
Authors:Le Han  Weijun He  Huixin Yan  Xianglan Li  Chengmin Wang  Qiumei Shi  Tiezhong Zhou  Guoying Dong
Affiliation:1. College of Global Change and Earth System Science, Beijing Normal University, Beijing, China;2. Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou, China;3. College of Animal Science and Technology, Hebei Normal University of Science and Technology, Hebei, China;4. College of Animal Husbandry and Veterinary, Jinzhou Medical University, Jinzhou, China
Abstract:
To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin genes originate from JS/1/00-like sublineage, neuraminidase genes originate from BJ/94-like sublineage, PB1, PA, NP, and NS genes all come from SH/F/98-like sublineage, PB2 genes originate from ST/163/04-like sublineage, while M genes come from G1-like sublineage. Genotype analysis showed that our isolates were classified as genotype 57. Molecular analyses indicated that our strains contained specific sites characteristic of low-pathogenic viruses. The current study once again highlights the necessity for continued surveillance of novel H9N2 viruses.
Keywords:genotype analysis  H9N2 influenza virus  molecular analyses  phylogenetic analyses
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