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E-cadherin is downregulated in benign prostatic hyperplasia and required for tight junction formation and permeability barrier in the prostatic epithelial cell monolayer
Authors:Feng Li  Laura E. Pascal  Donna B. Stolz  Ke Wang  Yibin Zhou  Wei Chen  Yadong Xu  Yule Chen  Rajiv Dhir  Anil V. Parwani  Joel B. Nelson  Donald B. DeFranco  Naoki Yoshimura  Goundappa K. Balasubramani  Jeffrey R. Gingrich  Jodi K. Maranchie  Bruce L. Jacobs  Benjamin J. Davies  Ronald L. Hrebinko  Joel D. Bigley  Dawn McBride  Peng Guo  Dalin He  Zhou Wang
Affiliation:1. Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China

Department of Urology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;2. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;3. Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;4. Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China

Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;5. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China;6. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Department of Urology, The Second Affiliated Hospital of Centre West University, Changsha, Hunan, China;7. Department of Urology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China;8. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;9. Pittsburgh Institute for Neurodegenerative Diseases, Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;10. Department of Epidemiology, Epidemiology Data Center, University of Pittsburgh, Pittsburgh, Pennsylvania

Abstract:
Keywords:benign prostate hyperplasia  E-cadherin  permeability  tight junction
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