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miRNA与热应激的关系及检测方法进展
引用本文:郭文晋,连帅,李悦,翟骏飞,张宇辰,郭景茹,计红,甄莉,杨焕民. miRNA与热应激的关系及检测方法进展[J]. 实验动物与比较医学, 2016, 24(6): 666-669
作者姓名:郭文晋  连帅  李悦  翟骏飞  张宇辰  郭景茹  计红  甄莉  杨焕民
作者单位:黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000;黑龙江八一农垦大学动物科技学院, 黑龙江 大庆 163000
基金项目:国家自然基金项目资助(批准号:31372398);教育部博士点导师基金(编号:20132305110004);黑龙江省自然科学基金面上项目(C2015041);黑龙江省教育厅重点实验室开放课题(AMKL201302)。
摘    要:热应激是机体长期暴露在热环境中无法充分将体内的热散出而导致机体温度失衡的一种状态。随着miRNA检测技术的进步,许多学者发现,热应激会导致miRNA的表达量发生变化。miRNA可以通过结合其靶基因,抑制miRNA靶基因的表达,从而在调控机体生命活动和抗热应激中发挥重要作用。

关 键 词:热应激  miRNA  靶基因  抗热应激
收稿时间:2016-05-24

Development of detection methods and relationship between miRNA and heat stress
GUO Wen-jin,LIAN Shuai,LI Yue,ZHAI Jun-fei,ZHANG Yu-chen,GUO Jing-ru,JI Hong,ZHEN Li and YANG Huan-min. Development of detection methods and relationship between miRNA and heat stress[J]. Laboratory Animal and Comparative Medicine, 2016, 24(6): 666-669
Authors:GUO Wen-jin  LIAN Shuai  LI Yue  ZHAI Jun-fei  ZHANG Yu-chen  GUO Jing-ru  JI Hong  ZHEN Li  YANG Huan-min
Affiliation:College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China;College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing Heilongjiang 163000, China
Abstract:Heat stress which leads to a state of temperature imbalance caused by long-term exposure of the body in a thermal environment and the body could not adequately dissipate heat. With the progress of the miRNA measurement technology, many scholars had found that heat stress can lead to a change in the miRNA. expression miRNA can bind its target genes to inhibit the expression of its target genes. That made miRNA to play an important role in the regulation of the body''s life activities and anti-heat stress.
Keywords:Heat Stress  miRNA  Target genes  Anti-heat stress
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