The role of vascular endothelial growth factor in ossification |
| |
| Authors: | Yan-Qi Yang Ying-Ying Tan Ricky Wong Alex Wenden Lin-Kun Zhang A Bakr M Rabie |
| |
| Affiliation: | 1.Department of Orthodontics, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China;2.Unit Pakar Ortodontik, Klinik Pergigian, Poliklinik Komuniti Mak Mandin, Malaysia;3.Department of Orthodontics, Tianjin Stomatological Hospital of Nankai University, Tianjin, China;4.Private Practice |
| |
| Abstract: | Osteogenesis and angiogenesis are two closely correlated processes during bone growth, development, remodelling and repair. Vascular endothelial growth factor (VEGF) is an essential mediator during the process of angiogenesis. Based on an extensive literature search, which was carried out using the PubMed database and the keywords of osteogenesis, VEGF, endochondral ossification and intramembranous ossification, this manuscript reviews the role of VEGF in ossification, with emphasis on its effect in endochondral and intramembranous ossification. Osteogenesis and angiogenesis are closely correlated processes. VEGF acts as an essential mediator during these processes. It not only functions in bone angiogenesis but also in various aspects of bone development. |
| |
| Keywords: | endochondral ossification intramembranous ossification osteogenesis vascular endothelial growth factor |
| 本文献已被 CNKI 等数据库收录！ |
|
