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滤泡辅助性T细胞与相关疾病研究进展
引用本文:周建伟,孔翠.滤泡辅助性T细胞与相关疾病研究进展[J].国际免疫学杂志,2012,35(5):350-353.
作者姓名:周建伟  孔翠
作者单位:1. 济宁医学院附属医院检验科,272029
2. 济宁医学院附属医院心内科
基金项目:基金项目:山东省高等学校科技计划资助项目(J11LF18);济宁市科技局科技发展计划资助项目(济科字[2011]57)
摘    要:滤泡辅助性T细胞(Tfh)是近几年发现的一种新的T细胞亚群,与Th1细胞、Th2细胞、Th17细胞及调节性T细胞(Tr)相互促进或拮抗,维持免疫系统的正常生理功能,其主要功能是辅助B细胞分化、发育和促进体液免疫应答,当Tfh细胞数量或功能紊乱时可引起自身免疫病、免疫缺陷病、肿瘤或感染性疾病的发生或加重.

关 键 词:滤泡辅助性T细胞  相关疾病

Study status of T follicular helper cells and the associated diseases
ZHOU Jian-wei , KONG Cui.Study status of T follicular helper cells and the associated diseases[J].International Journal of Immunology,2012,35(5):350-353.
Authors:ZHOU Jian-wei  KONG Cui
Institution:. Clinical Laboratory, the Affiliated Hospital of Jining University, Jining 272029, China
Abstract:T follicular helper cell is a newly found subpopulation of the T cells. This type of T cells maintains the normal function of immune system together with other T subsets. The main function of T follicular helper cell is to improve B-cell differentiation and humoral immune. It is also related with autoimmune diseases, immunodeficiency, tumor and infectious diseases.
Keywords:T follicular helper cells  Associated diseases
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