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| 717型阴离子交换树脂分离猫豆中的猫豆胍 | |
| 引用本文： | 黄增琼,蒋伟哲,黄兴振,巫世红,陆璐. 717型阴离子交换树脂分离猫豆中的猫豆胍[J]. 中国药业, 2009, 18(12): 23-24 |
| 作者姓名： | 黄增琼 蒋伟哲 黄兴振 巫世红 陆璐 |
| 作者单位： | 1. 广西医科大学药学院,广西,南宁,530021;右江民族医学院药学系,广西,百色,533000 2. 广西医科大学药学院,广西,南宁,530021 |
| 基金项目： | 国家自然科学基金，广西自治区科学基金，广西研究生教育创新计划 |
| 摘 要： | 目的考察717型阴离子交换树脂分离猫豆中猫豆胍（MDG）的工艺参数。方法以猫豆胍洗脱率为考察指标，应用正交试验法考察洗脱液浓度、用量和洗脱速度对洗脱效果的影响。结果在考察范围内，最佳分离条件为50倍量1％氨水、洗脱速度3．0mL／min。在此优化条件下，洗脱率为63．46％。结论该工艺方法简单，成本低廉，但效率低，不适合于工业化大生产。 |
| 关 键 词： | 猫豆 猫豆胍 离子交换 阴离子树脂 分离纯化 |
Separation of MDG from Seed of Stizolobium Cochinchinensisby 717 Antion Exchange Resin |
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| Huang Zengqiong,Jiang Weizhe,Huang Xingzhen,Wu Shihong,Lu Lu. Separation of MDG from Seed of Stizolobium Cochinchinensisby 717 Antion Exchange Resin[J]. China Pharmaceuticals, 2009, 18(12): 23-24 | |
| Authors: | Huang Zengqiong Jiang Weizhe Huang Xingzhen Wu Shihong Lu Lu |
| Affiliation: | 1. Pharmaceutical School, Gnangxi Medical University, Nanning, Guangxi, China 530021; 2. Department of Pharmacy, Youjiang Medical College for Nationality, Baise, Guangxi, China 533000) |
| Abstract: | Objective To study the process parameters of MDG separated from the seed of Stizolobium cochinchinensis by 717 antion exchange resin. Methods The orthogonal test was adopted to study the eluting effect of MDG with the elution rate as the index, and concentration of eluant, amount, elution velocity as the influence factors. Results The best separating conditions were 50 times of 1% ammonia hydrate as eluant, and the elution velocity was 3.0 mL/min. Under the optimal conditions, the elution rate was 63.46%. Conclusion The separated procedure is simple, and the cost is cheap, but it is low efficiency and unsuited for industrial large scale production. |
| Keywords: | seed of Stizolobium cochinchinensis MDG ion exchange antion resin separation and purification |
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