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Leber遗传性视神经病变的治疗学研究进展
引用本文:周和政,金中秋,吴建国. Leber遗传性视神经病变的治疗学研究进展[J]. 国际眼科杂志, 2003, 3(4): 84-86
作者姓名:周和政  金中秋  吴建国
作者单位:430070,中国武汉广州军区武汉总医院眼科;430070,中国武汉广州军区武汉总医院眼科;430070,中国武汉广州军区武汉总医院眼科
摘    要:既往认为Leber遗传性视神经病变(LHON)无特殊治疗,但随着病因病机研究的进展,相继推出了一些相应的治疗手段。本文简要介绍了与慢性氰化物中毒学说、视交叉部蛛网膜炎症学说及线粒体DNA突变学说相应的治疗学研究进展。

关 键 词:Leber遗传性视神经病变  治疗学  氰化物中毒  视交叉部蛛网膜炎  线粒体DNA
修稿时间:2003-05-12

Research advances in treatment of Leber''''s hereditary optic neuropathy
H e-Zhen g Zhou,Zhong-Qiu Jin,Jian-Guo Wu. Research advances in treatment of Leber''''s hereditary optic neuropathy[J]. International Eye Science, 2003, 3(4): 84-86
Authors:H e-Zhen g Zhou  Zhong-Qiu Jin  Jian-Guo Wu
Affiliation:H e-Zhen g Zhou,Zhong-Qiu Jin,Jian-Guo Wu. Department of Ophthalmology,Wuhan General H ospital of Guangzhou Military Command,Wuhan 430070,Hubei Province,China
Abstract:It was believed that there was no special therapy for Leber's heredita ry optic neuropathy. However, some treatments have been recommended thanks to th e advance in its pathogenic researches in recent years. This paper makes a brief introduction of the therapeutic approaches respectively corresponding to the th eory of chronic cyanide toxicosis, that of arachnoid inflammation on optical chi asma and that of mutation of mitochondrial DNA.
Keywords:Leber's hereditary optic neuropathy  therapeutics  cyanide toxicosis  arachnoid inflammation on optical chiasma  mutation of mitochondrial DNA
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