肝内胆管癌的诊断与治疗(附12例报告)

目的探讨肝内胆管癌发病的诊治方法。方法对我院1990年1月至2003年3月经手术和病理证实的12例肝内胆管癌病例资料进行回顾性分析。结果早期症状无特异性，AFP检查均为阴性，血CEA检查升高显著3例，4例术前诊断为肝内胆管癌，8例误诊，本组行根治性切除5例(41．6％)，姑息性手术7例。结论肝内胆管癌误诊率高，根治性手术率低，熟悉本病的临床特征，B超检查仍是首选方法。术中病理学检查是避免误诊漏诊的重要方法，根治性手术切除是本病最有效的治疗方法。

Diagnosis and treatment of intrahepatic cholangiocarcinoma:a report of 12 cases

Objective To investigate the diagnosis and treatment of intrahepatic cholangiocarcinoma (IC). Methods The data of 12 cases of pathologically confirmed IC receiving operation in our hospital from January 1990 to March 2003 were retrospectively analyzed. Results In the early stage, no specific symptoms were found and AFP was negative in all the 12 cases and CEA significantly increased in only 3 cases. Four cases were diagnosed as suffering from IC and the others were misdiagnosed. Of all the 12 patients, 5 (41.6%) underwent radical resection and 7 received palliative excision. Conclusions The rate of misdiagnosis was high but that of radical resection low for IC. Knowing its clinical features well, preoperative B-US and intraoperative biopsy are important to avoid misdiagnosis. Radical resection is the best way for treatment of IC.