等离子电切联合灌注透明质酸钠治疗腺性膀胱炎疗效观察

目的:探讨膀胱等离子电切联合灌注透明质酸钠治疗腺性膀胱炎的临床效果。方法:26例腺性膀胱炎患者,随机分A、B两组,每组13人,均采用经尿道等离子电切膀胱炎性黏膜;A组术后不做任何治疗,B组13例术后两周予透明质酸钠溶液40mg膀胱灌注治疗:每周1次,连续4周,再每月1次,连续4月。评估患者治疗前,治疗第6周及第6月的血尿症状,疼痛评分,排尿次数,夜尿次数,残余尿和最大尿流率各项评价指标。结果:患者治疗后均获6~12个月随访。观察组(B组)患者术后症状缓解显著优于对照组(A组),治疗第6周及第6月,B组术后灌注透明质酸钠溶液患者的血尿症状、疼痛评分、残余尿和最大尿流率各项评价指标分别与对照组A组相比较差异有统计学意义(均P<0.05)。所有随访患者未见复发。结论:膀胱内灌注透明质酸钠液结合等离子电切治疗腺性膀胱炎显著改善膀胱刺激症状及排尿功能,未见明显并发症。

Curative effect of sodium hyaluronate combined with transurethral plasmakinetic resection in cystitis glandularis

Objective: To investigate the efficacy of intravesical instillation of sodium hyaluronate for the treatment of cystitis glandularis (CG) aftertransurethral plasmakinetic resection.Methods: Twenty-six cases who underwent transurethral plasmakinetic resection in Bladder mucosa were randomly divided into two groups. There were 13 cases in each group, no medicine intravescal instillation for group A and sodium hyaluronate for group B. The patients in group B were given instillation of sodium hyaluronate therapy after two weeks from the operation once a week for four times, and then once a month for also four times. Hematuria, odynuria degree score, micturition frequency, nocturia frequency, residual urine and the maximal urine lfow rate were assessed at baseline , after 6 weeks and 6 months.Results: The follow-up time was 6~12 months. All patients had no recurrence. The relief symptom in groupB was signiifcantly better than that in the group A, the symptoms of hematuria, odynuria degree score, residual urine and maximum urine lfow rate of the B group were signiifcantly different from those of the control group (P<0.05). No recurrence was found in all patients during follow-up period. Conclusion:The treatment of cystitis glandular cystitis with sodium hyaluronate after transurethral plasmakinetic resection signiifcantly improved the symptoms of bladder irritation and urination function.There is no signiifcant complications.