FLUORIDE IN HUMAN MILK |
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| Authors: | C. J. SPAK L. I. HARDELL P. DE CHATEAU |
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| Affiliation: | Department of Cariology and Pharmacology, School of Dentistry, Karolinska Institute, Stockholm, Department of Paediatrics, University Hospital, Uppsala, Department of Paediatrics, Karolinska Hospital, Stockholm, Sweden |
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| Abstract: | ABSTRACT. Reported contents of fluoride (F) in human milk vary considerably. The aim of this study was to determine the F content in human milk under different levels of F intake using a silicon-facilitated microdiffusion technique, which had a good accuracy and precision. The mean F concentration of colostrum from mothers in a 1.0 ppm and a 0.2 ppm F area was 0.36±0.02 μmol/I (± SEM) and 0.28±0.02 μmol/I, respectively. The mean F concentration of mature milk from a 1.0 ppm F area was 0.37±0.04 μmol/I. Within the 1.0 ppm F area, the intra- and interindividual differences in F concentration were very small. No statistically significant difference in milk F concentration between the two areas was found. Consequently, breastfed infants living in a 1 ppm or a 0.2 ppm F area will have an approximately equal F intake of 5-10 μg per day, in spite of great differences in F intake among the nursing mothers. |
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| Keywords: | Fluoride human milk infants |
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