石棉工人接尘量与肺癌发病关系的研究

对北京市制动密封材料厂的1244名接尘职工(其中13名死于肺癌),用寿命表法和Logistic回归模型进行接尘量与肺癌发病关系的研究表明,肺癌发病概率与累积接尘量之间呈直线相关。若以工作30或40年,死亡概率以12/10万或19/10万计算,则年平均粉尘浓度在0.73 ～1.70mg/m~3(寿命表法,40年)和0.03～2.11mg/m~3(Logistic回归模型,30年)之间,其对应的纤维计数浓度为1.37～1.54f/ml和1.25～1.61f/ml。作者建议作业场所现行石棉最高容许浓度应该进一步降低。

DOSE-RESPONSE RELATIONSHIP BETWEEN ASBESTOS EXPOSURE AND INCIDENCE OE LUNG CANCER

In this study 1244 workers (among them 13 cases of lung cancer) of Beijing brake sealing material factory (previous Beijing asbestos products factory) were investigated and the dose-response relationship between asbestos exposure and incidence of lung cancer was studied.The results had shown that the relationship was in positive correlation. If a man worked 30 or 40 years and the probability of incidence will be lower than 12/105 (taken from a survey of fatal cause of malignant cancer for men in big-cities of China, 1973-1975) or 19/105 (taken from a survey of cancer mortality in Beijing urban area, 1976-1979) .The yearly average concentration of asbestos dust should be at the range of 0.73-1.70 mg/m3(using method of life-table, 40 yrs) and 0.03-2.11 mg/m3 (using Logistic regression model, 30 yrs) . The gravimetrical dust concentrations were converted into fibre counting concentrations according to a study on relationship between fibre and mass concentration.The corresponding fibre counting concentration were 1.37-1.54 f/ml and 1.25-1.61 f/ml.Authers propose that hygienic standard (maximum allowable concentration for asbestos chrysotile in the workplace air should be further reduced.