In vitro activity of azithromycin against clinical isolates of Legionella species. |
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| Authors: | P H Edelstein and M A Edelstein |
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| Affiliation: | Department of Pathology, University of Pennsylvania, School of Medicine, Philadelphia 19104-4283. |
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| Abstract: | The activities of azithromycin, erythromycin, and ciprofloxacin against 21 Legionella isolates were measured by an agar dilution method and in macrophages. The MICs for 90% of strains tested were 2.0, 1.0, and 0.5 micrograms/ml for azithromycin, erythromycin, and ciprofloxacin, respectively. Azithromycin and ciprofloxacin were both bactericidal in the macrophage system, but erythromycin was bacteriostatic. |
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