甲状腺结节与其他实体瘤并存的临床诊治

目的：调查实体肿瘤患者中甲状腺结节的发生率和恶性率，探讨甲状腺结节与原发恶性肿瘤的关系及对其诊治的影响。方法：收集安徽医科大学第二附属医院肿瘤中心2016年1月1日—3月31日所有住院患者作为实体瘤组，进行甲状腺彩超、促甲状腺激素（TSH）检测，并与同时期性别、年龄相似的健康体检人群（对照组）相比较。统计甲状腺结节的发生情况，分析其与实体肿瘤的关系及对诊治的影响。结果：两组中女性甲状腺结节发病率均高于男性；与对照组相比，实体肿瘤组中甲状腺结节的总发病率及甲状腺多发结节发病率较高（P＜0.05）；实体肿瘤组和对照组的甲状腺结节直径多在1 cm以下。实体肿瘤组并存的甲状腺结节恶性率较高（23.53%），乳腺癌是并发甲状腺结节最多的实体肿瘤。甲状腺结节对实体肿瘤患者临床诊治无影响104例（65.00%），轻度影响46例（28.75%），中度影响6例（3.75%），重度影响4例（2.50%）。结论：实体肿瘤中并存的甲状腺结节发病率及恶性率均较高，在临床中应该受到重视。甲状腺结节对实体肿瘤诊治的影响与原发病的情况有关。全面检查甲状腺可能对病情复杂的肿瘤诊治有很大帮助。

Clinical Investigation of Thyroid Nodules with Other Concomitant Solid Tumors

Objective: To investigate the incidence and effects of thyroid nodules in patients with primary malignant tumors. Methods: From January 2016 to March 2016, all hospitalized patients with solid malignant tumors in the Second Affiliated Hospital of Anhui Medical University were collected as the solid tumor group, and healthy examination population with similar gender and age during that period were used as the control group. Both groups performed thyroid ultrasound and TSH examination, and the relationship between thyroid nodules and solid tumors was analysized. Results: The overall incidence of thyroid nodules and incidence of multinodules in the solid tumor group were higher than the control group (p<0.05), and most nodules were less than 1cm. The solid tumor group had a higher malignant rate of thyroid nodules (23.53%), and breast cancer was the most common solid tumor among these patients with thyroid nodules. No influence of thyroid nodules on the solid tumor was observed in 104 patients (65.00%), minimal influence was noted in 46 patients (28.75%), moderate influence was found in 6 patients (3.75%) and major influence was found in 4 patients (2.50%). Conclusions: The incidence and malignancy rate of thyroid nodules in patients with solid tumors were higher than the healthy people. A complete examination of the thyroid gland may be of great help to the diagnosis and treatment of the primary solid tumors especially the complicated tumors.