院内葡萄球菌的感染及耐药研究

目的了解院内葡萄球菌的感染分布及耐药变迁状况。方法回顾分析2005年至2007年3年间葡萄球菌的感染状况，按CLSI K-B纸片法标准，测定并判读葡萄球菌的耐药趋势，同时用纸片法监测耐甲氧西林的葡萄球菌（MRS）耐药表型。结果葡萄球菌的感染主要来自下呼吸道（49．5％）和伤口（27．5％）感染；分离的葡萄球菌以金黄色葡萄球菌（42．1％）、人葡萄球菌（19．5％）及溶血葡萄球菌（15．4％）为主，同时耐甲氧西林葡萄球菌（MRS）有较高的检出率，从2004年的29．2％快速上升到2007年的89．6％。所检出的葡萄球菌除对万古霉素及替考拉宁100％的敏感外，对多种抗菌药物呈现多多重的耐药性。结论葡萄球菌以下呼吸道和伤口感染为主，其MRS感染率呈现逐年回升之势，MRS的感染及多重耐药性应引起高度重视，合理及严格控制抗生素的使用对减少高耐菌株的产生和流行至关重要。

Investigate of infection and drug resistance of staphylococcus on bosocomial infections

Objective To study the methods of treatment the maxillofacial fracture, and analysis the rigid internal fixation. Methods Patients with the maxillofacial fracture in five years were divided into two the group of rigid internal fixation and the group of traditional treatment. The information of two groups are compared and analysis with a standard. Results The complications of the group of rigid internal fixation are less than that of the group of traditional treatment. Conclusion The rigid internal fixation is great helpful to resume the max-illofacial form and function.