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Intravitreal bevacizumab in aggressive posterior retinopathy of prematurity.
Authors:António Travassos  Susana Teixeira  Pinto Ferreira  Isaura Regadas  Ana Sofia Travassos  Florindo Esteves Esperancinha  Isabel Prieto  Grapa Pires  Robert van Velze  A Valido  Maria do Céu Machado
Affiliation:Pediatric Retina Department, Ophthalmology Service, Hospital Fernando Fonseca, Lisbon, Portugal.
Abstract:
The anatomic response to intravitreal bevacizumab injection in three patients with aggressive, posterior retinopathy of prematurity is described. In all cases, the worse eye was treated with a single intravitreal injection of 0.75 mg of bevacizumab as monotherapy or complementary to laser therapy. In 24 hours, all injected eyes showed regression of the tunica vasculosa lentis and iris vessel engorgement and disappearance of iris rigidity. In addition, plus disease and retinal proliferation began to regress. None of the eyes required additional treatment. Follow-up of up to 10 months
Keywords:
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