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Porcine acellular dermal matrix for delayed abdominal wall closure after pediatric liver transplantation
Authors:O. Caso Maestro  M. Abradelo de Usera  I. Justo Alonso  J. Calvo Pulido  A. Manrique Municio  F. Cambra Molero  A. García Sesma  C. Loinaz Segurola  E. Moreno González  C. Jiménez Romero
Affiliation:Department and Institution, General Surgery and Abdominal Organ Transplantation, Hospital 12 de Octubre, , Madrid, Spain
Abstract:
Children are one of the groups with the highest mortality rate on the waiting list for LT. Primary closure of the abdominal wall is often impossible in the pediatric population, due to a size mismatch between a large graft and a small recipient. We present a retrospective cohort study of six pediatric patients, who underwent delayed abdominal wall closure with a biological mesh after LT, and in whom early closure was impossible. A non‐cross‐linked porcine‐derived acellular dermal matrix (Strattice? Reconstructive Tissue Matrix; LifeCell Corp, Bridgewater, NJ, USA) was used in all of the cases of the series. After a mean follow‐up of 26 months (21–32 months), all patients were asymptomatic, with a functional abdominal wall after physical examination. Non‐cross‐linked porcine‐derived acellular dermal matrix (Strattice?) is a good alternative for delayed abdominal wall closure after pediatric LT. Randomized controlled trials are necessary to determine the best moment and the best technique for abdominal wall closure.
Keywords:liver transplantation  hernia  partial liver grafts  pediatric transplantation
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