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Bone Morphogenetic Protein‐2 and Vascular Endothelial Growth Factor in Bone Tissue Regeneration: New Insight and Perspectives
Authors:Rajendra Aryal MD  Xiao‐peng Chen MD  Cheng Fang MD  Yong‐cheng Hu MD  PhD
Affiliation:1. Tianjin Medical University, , Tianjin, China;2. Department of Bone Oncology, Tianjin Hospital, , Tianjin, China
Abstract:
The study of bone tissue regeneration in orthopaedic diseases has stimulated great interest among bone tissue engineering specialists and orthopaedic surgeons. Combinations of biomaterials, growth factors and stem cells for repairing bone have been much studied and researched, yet remain a challenge for both scientists and clinicians pursuing regenerative medicine. The purpose of this review was to elucidate the role of sequential release of bone morphogenetic protein‐2 and vascular endothelial growth factor in producing better outcomes in the field of bone tissue regeneration.
Keywords:Bone morphogenetic protein‐2  Bone tissue regeneration  Vascular endothelial growth factor
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