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Participation of mouse T and B lymphocytes in the graft versus host reaction
Authors:M. S. Blyakher
Abstract:Transplantation of spleen or lymph node cells from CBA mice into sublethally irradiated (CBAxC57BL/6)F1 mice induced the development of a graft versus host reaction (GVHR). The lymphocytes lost their ability to give this reaction after treatmentin vitro with specific sera against both mouse T lymphocytes and B lymphocytes. The development of the GVHR in mice is evidently connected with cooperative interaction between T and B lymphocytes.Department of Immunology, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR Yu. M. Lopukhin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 6, pp. 713–715, June, 1976.
Keywords:T and B lymphocytes  graft versus host reaction  cellular interaction
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