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恶性脑胶质瘤手术后力尔凡增效放疗的临床研究
引用本文:步星耀,赵红卫,张永福,李太平,梁庆华,王勇,薛绛宇. 恶性脑胶质瘤手术后力尔凡增效放疗的临床研究[J]. 河南医学研究, 2004, 13(3): 236-238
作者姓名:步星耀  赵红卫  张永福  李太平  梁庆华  王勇  薛绛宇
作者单位:河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003;河南省人民医院神经外科,河南,郑州,450003
摘    要:目的:探讨恶性脑胶质瘤手术后力尔凡增效放疗的临床效果。方法:恶性脑胶质瘤78例手术后随机分为治疗组(力尔凡加放疗)46例,对照组(单纯放疗)32例,进行随访分析,研究近期疗效,生存率和生存期、机能状态、免疫功能及复发率。结果:治疗组有效率76.08%,3年生存率为58.8%;对照组近期疗效有效率43.8%,3年生存率为29.4%。两组近期疗效有效率和3年生存率差异均有显著差异(P<0.01)。结论:力尔凡能增强胶质瘤术后放疗的敏感性,并提高生存率。

关 键 词:脑胶质瘤  术后放疗  力尔凡
文章编号:1004-437X(2004)03-0236-03
修稿时间:2004-04-06

Clinical analysis of sensitive radiotherapy concurrent with Lifein for postoperative malignant glioma patients
BU Xing-yao,ZHAO Hong-wei,ZHANG Yong-fu,LI Tai-ping,LIANG Qing-hua,WANG Yong,XUE Jing-yu. Clinical analysis of sensitive radiotherapy concurrent with Lifein for postoperative malignant glioma patients[J]. Henan Medical Research, 2004, 13(3): 236-238
Authors:BU Xing-yao  ZHAO Hong-wei  ZHANG Yong-fu  LI Tai-ping  LIANG Qing-hua  WANG Yong  XUE Jing-yu
Abstract:Objective: To evaluate the effects and safety of Lifein concurrent with radiotherapy in the treatment of postoperative malignant glioma. Methods: 78 patients with glioma were divided into two groups randomly, 46 cases in group Ⅰ were treated with lifein and radiotherapy, and 32 in group Ⅱ were treated with radiotherapy only. Results : The recent efficiency and the survival rate of three years in group Ⅰ were 76.08% and 58.8%, respectively,compared with those 43.75% and 29.4% in group Ⅱ (P < 0.01) . Conclusion : Combination of Lifein and Radiotherapy shows remarkable effect in the treatment of glioma and can enhance survival rate of these patients.
Keywords:glioma  radiotherapy  Lifein
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