牙菌斑生物膜模型的研究进展

牙菌斑生物膜是龋病和牙周病的主要致病因素,也是目前口腔微生物学和生态学研究的热点.研究者们建立了多种模型以研究菌斑生物膜的发生机制和发生过程.龈上菌斑和龈下菌斑的生存环境及其内的微生物群有明显差异,故模型系统也各不相同.龈上菌斑易于收集且其生存环境易于模拟,目前已有多种体内和体外模型被用于龈上菌斑生物膜的研究,而龈下菌斑生物膜模型的研究相对较少.本文就牙菌斑生物膜模型的最新研究进展作一综述.

Research progress on models of dental plaque biofilm

Dental plaque biofilm is one of key etiological factors of dental caries and periodontal diseases, and is also the hotspot of oral microbiology and ecology. Researchers have developed various models to study mechanisms and courses of their formation. The living environment of subgingival plaque and supragingival plaque is obviously different, as well as their incumbent microbial populations. As a result, the model system is different. Supragingival plaque is easy to be collected and the living environment i...