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脑钠肽在COPD合并肺心病急性发作中的研究
引用本文:周雨田,马骄. 脑钠肽在COPD合并肺心病急性发作中的研究[J]. 医学理论与实践, 2013, 26(5): 571-572
作者姓名:周雨田  马骄
作者单位:周雨田 (四川省人民医院干部科老年疾病研究所呼吸病房,四川省成都市,610072); 马骄 (成都医学院检验医学院);
摘    要:目的:探讨血脑钠肽水平在肺源性心脏病患者急性发作时及治疗后2周的变化并分析其临床意义。方法:75例COPD合并肺心病急性发作期患者在常规治疗前、后检测血中BNP及CRP水平及动脉血氧分压、二氧化碳分压。结果:治疗前的BNP及CRP水平均显著高于治疗后(P<0.01),治疗后PaO2较治疗前显著上升(P<0.05)。结论:COPD合并肺心病急性发作期患者血中BNP及CRP水平明显增高,可以作为急性发作及好转的指标。

关 键 词:慢性阻塞性肺疾病  肺心病  脑钠肽

Study on Brain Natriuretic Peptide in AECOPD and Chronic Cor Pulmonale Patients
ZHOU Yutian,MA Jiao. Study on Brain Natriuretic Peptide in AECOPD and Chronic Cor Pulmonale Patients[J]. The Journal of Medical Theory and Practice, 2013, 26(5): 571-572
Authors:ZHOU Yutian  MA Jiao
Affiliation:.*Department of Cadre Healthcare,Sichuan People’s Hospital,Chengdu City,Sichuan Province 610072
Abstract:Objective:To evaluate the level of BNP in patients with chronic obstructive pulmonary disease(COPD) and chronic cor pulmonale.Methods:Before and after 14 days therapy,plasma BNP levels and blood gas analysis were detected in 75 patients with COPD and chronic cor pulmonale.Results:The serum BNP,CRP level before therapy were significantly higher than that of afer therapy(P<0.01).After therapy,the PaCO2 level were significantly lower than pre-treatment(P<0.01),the PaO2 after therapy were significantly higher than pre-treatment(P<0.05).Conclusion:BNP and the CRP level in patients with acute COPD and chronic cor pulmonale were significantly higher.BNP and CRP level could be used as AECOPD and recovery index.
Keywords:COPD  Chronic Cor Pulmonale  Brain Natriuretic Peptide
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