| Abstract: | ![]()
Identical antigenic determinants were detected by immunofluorescence and the cytotoxic test on the surface of human erythrokaryocytes with the aid of antibodies against a specific antigen of mouse erythroblasts (EBAG) discovered previously during a study of Rauscher leukemia. The antigen is present on the membrane of most nucleated erythroid cells of the liver of human embryos in the early stages of development and in adult human bone marrow, but is not found in fetal thymocytes, neonatal kidney cells, adult human liver, or in peripheral blood erythrocytes. EBAG evidently possesses an interspecific determinant which is common for mammalian nucleated erythroid cells and which may serve as their specific marker.Laboratory of Immunochemistry and Diagnosis of Tumors, Oncologic Scientific Center, Academy of Medical Sciences of the USSR, Moscow. Department of Control of Virus Preparations, L. A. Tarasevich Institute of Standardization and Control of Medical Biological Preparations, Moscow. Department of Hematology, Central Postgraduate Medical Institute, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR L. M. Shabad.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 9, pp. 330–332, September, 1978. |
