氨氯地平、贝那普利联合治疗原发性高血压的疗效观察

目的探讨氨氯地平、贝那普利联合治疗原发性高血压的降压效果。方法将我院收治的100例原发性高血压患者随机分为观察组和对照组各50例,比较两组的降压效果及不良反应。结果观察组降压总有效率达92.0%,显著高于对照组(P<0.05)。观察组的SBP、DBP均较治疗前及对照组明显降低(P<0.05)。结论氨氯地平、贝那普利联合治疗原发性高血压具有协同降压的作用,降压效果确切,安全性好,值得推广和应用。

Effects of amlodipine combined with benazepril in treatment of primary hypertension

Objective To investigate the antihypertensive effect of amlodipine, benazepril treatment of essential hyperten- sion. Methods A total of 100 hypertensive patients in our hospital, all patients were randomly divided into two groups （amlodipine, benazepril combination therapy） and control group （amlodipine） 50 cases each, two groups were compared an- tihypertensive effect and adverse reactions. Results The observation group buck total effective rate was 92.0%, significantly higher than that in the control group （P 〈 0.05）. SBP of the observation group, of DBP than before treatment and control group was significantly lower （P 〈 0.05 ）. Conclusion Amlodipine, benazepril treatment of essential hypertension have syn- ergistic antihypertensive effect, the exact effect of step-down, security is good, worthy of promotion and application.