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富马酸喹硫平与齐拉西酮治疗精神分裂症的疗效比较
引用本文:雷旭伟,陈苏伟. 富马酸喹硫平与齐拉西酮治疗精神分裂症的疗效比较[J]. 海峡药学, 2008, 20(5): 73-74
作者姓名:雷旭伟  陈苏伟
作者单位:浙江省丽水市第二人民医院,丽水,323000;浙江省丽水市中医院,丽水,323,000
摘    要:
目的探讨思瑞康(富马酸喹硫平)与齐拉西酮对精神分裂症的临床疗效及其副作用。方法应用思瑞康与齐拉西酮进行对照研究,采用PANSS、TESS量表分别评定疗效和副反应。结果思瑞康与齐拉西酮疗效相似,思瑞康组显效率75%,齐拉西酮组显效率77.5%。结论思瑞康与齐拉西酮对精神分裂症均有较好的疗效,思瑞康在0.6g.d-1左右未见锥体外系副作用。

关 键 词:思瑞康(富马酸喹硫平)  齐拉西酮  精神分裂症
文章编号:1006-3765(2008)-05-0073-02

A comparative study between seroquel and ziprasidone In the treatment of schizophrenia
LEI Xu-wei,CHEN Su-wei. A comparative study between seroquel and ziprasidone In the treatment of schizophrenia[J]. Strait Pharmaceutical Journal, 2008, 20(5): 73-74
Authors:LEI Xu-wei  CHEN Su-wei
Abstract:
OBJECTIVE To investigate the clinical effects and side effects of seroquel and ziprasidone for treating schizophrenia.METHORDS A total of 80 patients were randomly divided into seroquel group and ziprasidone group.The clinical effects and side effects were evaluated with PANSS and TESS.RESULTS Curative effects and side effects of seroquel were similar to those of ziprasidone.The effective rate of seroquel group and ziprasidone group were 75% and 77.5%,respectively.CONCLUSION Seroquel and ziprasidone both have better curative effects on schizophrenia.
Keywords:Seroquel  Ziprasidone  Schizophrenia
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