噪声对大鼠T淋巴细胞亚群及其功能的影响

（目的）观察噪声暴露不同时间对大鼠T淋巴细胞群及其功能的影响。（方法）将大鼠暴露于100dB(A)噪声中，在不同的噪声暴露时间（1天，7天及21天）对大鼠T淋巴细胞亚群和淋巴细胞的增殖功能进行了检测。（结果）与对照组相比，接噪7天组CD8^ 细胞显著升高，接噪1天7天组CD4^ /CD8^ 比值显著低于对照组，在接噪的不同时间淋巴细胞增殖功能均降低。（结论）噪声暴露不同时间可引起淋巴细胞数量和功能的改变。

Effect of white noise on hamster T lymphocyte subpopulation and its function

[Purpose]To observe effect of different noise - exposed lengths on hamster T lymphocyte subpopulation and its functions. [Method]Hamsters were exposed to 100 dB(A) noise, then hamster T lymphocyte subpopulation and its proliferation function were detected in different exposed lengths (1,7 and 21 days). [Result]Compared with control group, CD8 cells of 7 - day group increased notably, CD4 /CD8 ratio of 1 - day group and 7 - day group were lower than that of control group notably; and lymphocyte proliferation function of different noise - exposed lengths all decreased. [Conclusion]Different noise - exposed length can cause changes in amount and function of lymphocyte.