NEUROTROPIN IMMUNOSTIMULATING ACTION ON
IMMUNOCOMPETENT CELLS |
| |
Authors: | G S Zhang F Y Hu Q Z Ye Y T Yan |
| |
Abstract: | Neurotropin (NSP) is an extract isolated from
the skin of rabbits inoculated with vaccinia virus.
The present study examines the possible action of
NSP on the number and function of immunocompe
tent cells in mice. The experiment showed that NSP
had no effect on both T and B lymphocytes of nor-
malimmunized mouse spleen. The degree of plaque
forming cell reaction and titre of specific antibody
showed no significant differences when the NSP
treated group and controls were compared. How-
ever, NSP exhibited promotive effect on specific
antigen binding cells in the early stage of immune
responses. It was also noted that the rosette forming
capacity of human T lymphocytes in vitro was restor-
ed markedly by NSP. These results suggest that
NSP possesses certain immunostimulating activity,
particularly on the specific antigen binding cells and
human T lymphocytes. |
| |
Keywords: | |
|
| 点击此处可从《中华医学杂志(英文版)》浏览原始摘要信息 |
| 点击此处可从《中华医学杂志(英文版)》下载免费的PDF全文 |