|
|||||
|
|
| 纳络酮可逆转急性心肌梗塞的压力反射钝化 | |
| 引用本文： | 何奔 王成海. 纳络酮可逆转急性心肌梗塞的压力反射钝化[J]. 中国药理学通报, 1996, 12(2): 174-175 |
| 作者姓名： | 何奔 王成海 |
| 作者单位： | 上海第二医科大学仁济医院心内科!上海200001(何奔，郑道声，邬亦贤，张世华)，第二军医大学神经生物学教研室!上海200433(王成海，林葆诚) |
| 摘 要： | 以大鼠急性心肌梗塞(AMI)模型,观察静脉及小脑延髓池注射纳络酮(Nal)对AMI前及AMI后lhBRS的影响,发现,无论AMI前后静脉及小脑延髓池给予Nal均有加强BRS作用.这一结果提示:Nal可能有助于AMIBRS钝化的逆转. |
| 关 键 词： | 纳络酮 急性心肌梗塞 压力反射敏感性 |
Naloxone can reverse blunted baroreflex sensitivity after acute myocardial infarction |
|
| HE Ben,ZHENG Dao-Sheng,WU Yi-Xian et al. Naloxone can reverse blunted baroreflex sensitivity after acute myocardial infarction[J]. Chinese Pharmacological Bulletin, 1996, 12(2): 174-175 | |
| Authors: | HE Ben ZHENG Dao-Sheng WU Yi-Xian et al |
| Abstract: | Acute myocardial infarction (AMI) model was made in SD rats by coronary ligation, the effects of naloxone (Nal) on the baroreflex sensitivity (BRS) were evaluated by administrated Nal intravenously (iv) and in-tracisternally (ic) before and after 1 h of AMI.Results showed that both pre and post AMI can Nal potentiate the BRS whether iv or ic. These results indicate that Nal may reverse the blunted BRS after AMI. |
| Keywords: | naloxone acute myocardial in-farction baroreflex sensitivity |
| 本文献已被 CNKI 维普 等数据库收录！ | |