Magnesium deficiency in drinking water modulates blood pressure, Ca and Mg distribution in tissues, and compartmentalization of membrane-bound calcium in platelets of normotensive WKY rats

Magnesium deficiency in drinking water increases calcium-accumulating capacity of the aortic and myocardial walls in normotensive WKY rats, induces Ca resorption from bones, and impairs compartmentalization of membrane-bound Ca in platelets, resulting in accumulation of Ca in the external plasma membrane without changing blood pressure. Increased systolic blood pressure was characteristic of rats in Ca-deficient groups. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 2, pp. 183–186, February, 1999