125例上皮性卵巢癌的预后分析

目的探讨上皮性卵巢癌的预后影响因素。方法回顾性分析2005年1月至2007年12月在江苏省肿瘤医院初诊的125例卵巢癌患者的临床资料,通过电话随访及患者返院复查的方式对患者病情变化进行追踪,随访统计截止日为2012年12月31日,分析患者年龄、肿瘤临床分期、病理类型、分化程度、术前辅助化疗、后残余肿瘤直径、化疗的总疗程数与预后的关系。结果患者年龄、肿瘤临床分期、术后残余肿瘤直径与患者的预后密切相关（P〈0．05）,病理类型、分化程度、化疗的总疗程数对预后无明显影响（P〉0．05）。结论卵巢癌患者的发病年龄、卵巢癌的临床分期、术后残留肿瘤的大小均可影响卵巢癌的预后,是卵巢癌的独立预后因素。所以,早期发现和诊断、彻底的手术治疗是改善其预后的根本。

Analysis of prognosis in 155 cases of epithelial ovarian carcinoma

Objective To assess prognostic factors impacted on overall survival in patients with epithelial ovarian carcinoma. Methods Clinical characteristics of 125 cases with stages Ⅰ -Ⅳ epithelial ovarian carcino- ma from Jan. 2005 to Dec. 2007, including ages, stages, the size of residues were analyzed retrospectively. Results The prognostic factors of epithelial ovarian carcinoma were related to ages, stages, the size of residues lesions（ P 〈0.05 ）. However, histological types, pathological differential grades, the number of chemotherapy circles were not related to the survival of epithelial ovarian carcinoma（ P 〉 0.05 ）. Conclusions The major in- dependent prognostic variables for epithelial ovarian carcinoma are stage, the size of residual tumor lesions. Therefore, the earlier diagnosis, the earlier surgery are the key points to improve the survival rates of epithelial ovarian carcinoma. Sufficient cycles and regular assistant chemotherapy are necessary for patients with epithelial ovarian cancer.