缬沙坦 卡维地洛 多巴胺联合治疗流行性出血热急性肾功能衰竭疗效观察

目的：探讨缬沙坦、卡维地洛及多巴胺联合治疗流行性出血热（ EHF ）急性肾功能衰竭的效果。方法将116例EHF急性肾功能衰竭患者随机分为对照组和治疗组各58例。对照组常规采用抗病毒、止血、维持内环境平衡，及早使用利尿剂、导泻等综合治疗；治疗组在常规综合治疗的基础上加用缬沙坦、卡维地洛及多巴胺。观察两组患者的疗效。结果治疗组尿蛋白消失快，进入多尿期早，尿素氮降至正常时间短，各种并发症低，透析病人数减少，能改善透析病人的预后，提高治愈率。结论缬沙坦、卡维地洛及多巴胺联合治疗EHF急性肾功能衰竭疗效显著。

Observation of the effects of valsartan, carvedilol and dopamine in the treatment of epidemic hemorrhagic fever patients with acute renal failure

Objective To investigate the therapeutic effects of valsartan , carvedilol and dopamine in the treatment of epidemic hemorrhagic fever （ EHF） patients with acute renal failure （ ARF） .Methods One hundred and sixteen EHF patients with ARF were randomly divided into the control group and the treatment group with 58 cases in each group .The control group received conventional therapy , including antiviral treatment , hemostatic treatment , maintaining internal environment balance , early use of diuretics , purgative therapy;the treatment group , on the basis of conventional therapy , was treated with valsartan ,carvedilol and dopamine .The curative effects of two groups were observed.Results Compared with the control group ,in the treatment group , urinary protein disappeared more quick-ly, the polyuric period appeared more early , the time of urea nitrogen returning to normal was shorter , the incidence of complications more lower ,the number of dialysis patients reduced , the outcomes of dialysis patients were better ,the cure rate was higher .Conclusion Valsartan, carvedilol and dopamine have significant efficacy in the treatment of EHF patients with ARF .