| 绝经期后妇女子宫内膜息肉中雌、孕激素受体表达特点及意义 |
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| 引用本文： | 张博,王建,张颖,曹引丽. 绝经期后妇女子宫内膜息肉中雌、孕激素受体表达特点及意义[J]. 医学争鸣, 2009, 0(24): 3142-3143 |
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| 作者姓名： | 张博 王建 张颖 曹引丽 |
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| 作者单位： | 渭南市中心医院妇产科;第四军医大学西京医院妇产科;陕西省妇幼保健院; |
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| 摘 要： | 目的：通过研究绝经后妇女子宫内膜息肉雌激素受体（ER）和孕激素受体（PR）的表达探讨其可能的发生机制及临床意义.方法：运用免疫组织化学方法检测并行半定量分析,对70例诊断子宫内膜息肉的绝经后妇女的内膜息肉及其邻近内膜组织中ER,PR的表达,并选用20例正常绝经后妇女的子宫内膜组织作为对照.结果：子宫息肉组腺体和间质内PR呈低水平表达,并明显低于对照组（P〈0.05）,其余各组中ER的表达无明显差异.结论：绝经后妇女PR的异常表达在子宫内膜息肉的发生中起重要作用.
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| 关 键 词： | 子宫内膜 息肉 雌激素受体 孕激素受体 |
Expression and significance of estrogen receptor and progesterone receptor in the endometrial polyps in postmenopausal women |
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| ZHANG Bo,WANG Jian,ZHANG Ying,CAO Yin-Li. Expression and significance of estrogen receptor and progesterone receptor in the endometrial polyps in postmenopausal women[J]. Negative, 2009, 0(24): 3142-3143 |
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| Authors: | ZHANG Bo WANG Jian ZHANG Ying CAO Yin-Li |
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| Affiliation: | ZHANG Bo1,WANG Jian2,ZHANG Ying2,CAO Yin-Li3 1Department of Obstetrics and Gynecology,Weinan Central Hospital,Weinan 714000,China,2Department of Obstetrics and Gynecology,Xijing Hospital,Fourth Military Medical University,Xi'an 710033,3Maternity and Child Care Hospital of Shaanxi Province,Xi'an 710003 |
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| Abstract: | AIM:To investigate the significance and possible mechanism of endometrial polyps(EP) in postmenopausal women by evaluating the expression and significance of estrogen receptor(EP) and progesterone receptor(PR).METHODS:Seventy postmenopausal women with EP,who were performed with endometrial biopsy and removing polyps,and 20 postmenopausal women with normal endometrium(EM) were as control group.The expression of ER and PR were evaluated by immunohistochemical method using a semiquantitative analysis.RESULTS:E... |
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| Keywords: | endomerium endometrial polyps estrogen receptor progesterone receptor |
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