| 氯吡格雷抵抗研究进展 |
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| 引用本文： | 齐晓云,杨关林. 氯吡格雷抵抗研究进展[J]. 心血管病学进展, 2006, 27(2): 208-210 |
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| 作者姓名： | 齐晓云 杨关林 |
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| 作者单位： | 1. 沈阳医学院沈洲医院心内科,辽宁,沈阳,110002
2. 辽宁中医学院附属医院,辽宁,沈阳,110032 |
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| 摘 要： | 氯吡格雷的抗血小板聚集作用在急性冠脉综合征和经皮冠状动脉介入术患者中得到广泛应用,但氯吡格雷抵抗的出现影响了其临床疗效。现就氯吡格雷抵抗的定义、临床意义、血小板聚集检测方法、发生机制及防治策略分别加以阐述。
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| 关 键 词： | 氯吡格雷 抵抗 血小板聚集 |
| 文章编号： | 1004-3934(2006)02-0208-03 |
| 收稿时间： | 2005-07-25 |
| 修稿时间： | 2005-07-25 |
Clopidogrel Resistance |
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| QI Xiao-yun,YANG Guan-lin. Clopidogrel Resistance[J]. Advances in Cardiovascular Diseases, 2006, 27(2): 208-210 |
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| Authors: | QI Xiao-yun YANG Guan-lin |
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| Affiliation: | 1. Department of Cardiology, Shengzhou Hospital Affiliated to Shengyang Medical College, Shengyang 110002, China ; 2. The Affiliated Hospital of Liaoning Traditional Chinese Medicine College, Shengyang 110032, China |
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| Abstract: | Although the action of anti-platelet aggregation of clopidogrel has been applicated extensively in patients with acute coronary syndromes and percutaneous coronary intervention,clopidogrel resistance restricts its clinical effecs. This article explained the concept,clinic significance,detecting method of platelet aggregation,possible mechanisms and prevention and treatment of clopidogrel resistance. |
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| Keywords: | clopidogrel resistance platelet aggregation |
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